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  • 产品名称:GRAPProteinLysate(GSTtagged)(Expressedinbacteria)

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  • 产品厂商:AvivaSysBio
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简单介绍:
GRAPProteinLysate(GSTtagged)(Expressedinbacteria)
详情介绍:
Characteristics Partial length GRAP is expressed in E. coli.
ProductDetails: Lysate Fraction Whole Cell Lysate
Lysate Type Protein Lysate
Alternative Name GRAP
Background This gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain.

Alias Symbols: MGC64880

Protein Interaction Partner: TRIM21, RBPMS, UBC, ARHGAP32, KHDRBS1, LAT, SHC1, SOS1, PLCG1, KIT, LCK, FYN, FASLG, EPOR, GAB2,
Molecular Weight 40 kDa
Gene ID 10750
NCBI Accession NM_006613, NP_006604
UniProt Q13588
Research Area Signaling
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 200 μL of distilled water. Final concentration is 1 mg/mL.
Concentration 1mg/mL
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.