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Background
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Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: V28, CCRL1, GPR13, CMKDR1, GPRV28, CMKBRL1
Protein Interaction Partner: CX3CL1,
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