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Background
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Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
Alias Symbols: L3, FLJ32384
Protein Interaction Partner: TCF12, CCDC36, HEXIM2, PRDM14, RNPS1, TADA3, SPRY2, SPRY1, PIN1, PIM1, MEOX2, GATA1, CDK9, RN7SK, HEXIM1, TERF2, TERF1, MEPCE, CCNT1,
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