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Background
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Interferons are cytokines that have antiviral effects and inhibit tumor cell proliferation. They induce a large number of genes in their target cells, including those coding for the guanylate-binding proteins (GBPs). GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). The protein encoded by this gene is a GTPase that converts GTP to GDP and GMP.
Alias Symbols: DKFZp451C2311
Protein Interaction Partner: CNDP2, NANS, RPS6KA1, PEPD, MVD, GSR, GNS, GLA, G6PD, CASP7, CAPN1, ASS1, GSK3B, GADD45A, CSNK2B, BNIP3L, BID, ANXA7, MAPK8IP2, STK3, KLHL20, BTBD2, LSM2, PAFAH1B3, PPP1R8, MAGI1, TFG, SERPINB9, SEPHS1, FXR1, HSPE1, SAT1,
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