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Background
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The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis.
Alias Symbols: PCTT, PSTI, TATI, Spink3, TCP
Protein Interaction Partner: NRSN1, TMPRSS15, CTRC, ELN,
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