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  • 产品名称：Toll-Interleukin1Receptor(TIR)DomainContainingAdaptorProtein(TIRAP)(InternalReg

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  • 产品厂商：ProSci-Inc
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简单介绍：
Toll-Interleukin1Receptor(TIR)DomainContainingAdaptorProtein(TIRAP)(InternalRegion)Peptide
详情介绍：
Blocked Antibody anti-TIRAP antibody (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein) (Middle Region) (ABIN1031126)
Characteristics 20 amino acids near the center of human TIRAP.
Human
Application Notes TIRAP peptide is used for blocking the activity of TIRAP.
Restrictions For Research Use only
Format Liquid
Concentration 200 μg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
Background publications Cotteret, Jaffer, Beeser, Chernoff: "p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD." in: Molecular and cellular biology, Vol. 23, Issue 16, pp. 5526-39, 2003 (PubMed).

Yamamoto, Sato, Hemmi, Sanjo, Uematsu, Kaisho, Hoshino, Takeuchi, Kobayashi, Fujita, Takeda, Akira: "Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4." in: Nature, Vol. 420, Issue 6913, pp. 324-9, 2002 (PubMed).