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  • 产品名称：T-CellImmunoglobulinandMucinDomainContaining4(TIMD4)(C-Term)Peptide

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  • 产品厂商：ProSci-Inc
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简单介绍：
T-CellImmunoglobulinandMucinDomainContaining4(TIMD4)(C-Term)Peptide
详情介绍：
Blocked Antibody anti-TIMD4 antibody (T-Cell Immunoglobulin and Mucin Domain Containing 4) (C-Term) (ABIN1030736)
Characteristics 15 amino acids near the carboxy terminus of human TIM-4.
Human
Application Notes TIM-4 peptide is used for blocking activity of TIM-4.
Restrictions For Research Use only
Format Liquid
Concentration 200 μg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
Background publications Meyers, Chakravarti, Schlesinger, Illes, Waldner, Umetsu, Kenny, Zheng, Umetsu, DeKruyff, Strom, Kuchroo: "TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation." in: Nature immunology, Vol. 6, Issue 5, pp. 455-64, 2005 (PubMed).

Kaplan, Lewis, Shelden, Somers, Pavlic, McCune, Richardson: "The apoptotic ligands TRAIL, TWEAK, and Fas ligand mediate monocyte death induced by autologous lupus T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 10, pp. 6020-9, 2002 (PubMed).

Chicheportiche, Chicheportiche, Sizing, Thompson, Benjamin, Ambrose, Dayer: "Proinflammatory activity of TWEAK on human dermal fibroblasts and synoviocytes: blocking and enhancing effects of anti-TWEAK monoclonal antibodies." in: Arthritis research, Vol. 4, Issue 2, pp. 126-33, 2002 (PubMed).

Lynch, Wang, Lund, Chen, Leal, Wiley: "TWEAK induces angiogenesis and proliferation of endothelial cells." in: The Journal of biological chemistry, Vol. 274, Issue 13, pp. 8455-9, 1999 (PubMed).