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  • 产品名称：Hexyl-4-pentynoicacid(HPA)

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  • 产品厂商：ArborAssays
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简单介绍：
Hexyl-4-pentynoicacid(HPA)
详情介绍：
Characteristics Induces histone hyperacetylation
30 times lower IC50 than VPA
Protects against glutamate-induced excitotoxicity
Background HPA causes histone hyperacetylation and protect against glutamate induced excitotoxicity in cultured neurons. HPA is one of the most effective valproic acid derivatives in terms of teratogenic potential in mice, hyperacetylation of core histone 4 in treated F9 Cells, and one of the lowest concentrations of half-maximum effect in HDAC enzyme inhibition assays. Inhibits HDAC activity with an IC50 of 13 uM (VPA= 398 uM). An Arbor Assays EXCLUSIVE!!
CAS-No 96017-59-3
Restrictions For Research Use only
Storage RT/4 °C
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