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  • 产品名称：Ratanti-Mouse(Murine)IgD(HeavyChain)Antibody(Biotin)

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  • 产品厂商：BioLeaf
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简单介绍：
Ratanti-Mouse(Murine)IgD(HeavyChain)Antibody(Biotin)
详情介绍：
Clone 11-26c
Isotype IgG2a
Characteristics The antibody detects: heavy chain of mouse IgD
The monoclonal antibody 11-26 reacts with mouse IgD of all haplotypes (e.g., IgDa, IgDb, IgDc), and does not react with other immunoglobulin isotypes.1 11-26 does not induce proliferation of mature B cells in vitro,5 nor does in vivo injection of the monoclonal antibody have any effect on activation of mature B lymphocytes.
Purification Immunoaffinity chromatography
Research Area Stem Cells, Hematopoietic Progenitors, Secondary Antibodies
Application Notes Working Dilution:
1 μg/10^6 cells
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Buffer 0.5 mg in 1.0 mL of PBS / NaN3.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid cycles of freezing and thawing.
Product cited in: Koenigsberger, Peckl-Schmid, Zaborsky, Patzak, Kiefer, Achatz: "HPK1 associates with SKAP-HOM to negatively regulate Rap1-mediated B-lymphocyte adhesion." in: PLoS ONE, Vol. 5, Issue 9, 2010 (PubMed).

Background publications Nitschke, Kosco, K?hler, Lamers: "Immunoglobulin D-deficient mice can mount normal immune responses to thymus-independent and -dependent antigens." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 5, pp. 1887-91, 1993 (PubMed).