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  • 产品名称：TGF-betaActivatedKinase1/MAP3K7BindingProtein1(TAB1)Peptide

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  • 产品厂商：PromoCell
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简单介绍：
TGF-betaActivatedKinase1/MAP3K7BindingProtein1(TAB1)Peptide
详情介绍：
Blocked Antibody anti-TAB1 (TAK1 Binding Protein) antibody (ABIN1003245)
Characteristics 13 amino acids near the center of human TAB1.
Application Notes TAB1 peptide is used for blocking the activity of the Anti-TAB1 antibody . It usually blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37ºC.
Restrictions For Research Use only
Format Liquid
Concentration 200 µg/mL
Buffer Supplied in PBS pH 7.2 (10 mM NaH₂PO₄, 10 mM Na₂HPO₄, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice For products with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. The peptide solution should be gently mixed before use.
Storage -20 °C
Storage Comment Store at -20°C, stable for one year.
Expiry Date 12 months
Product cited in: Schimmer: "Inhibitor of apoptosis proteins: translating basic knowledge into clinical practice." in: Cancer research, Vol. 64, Issue 20, pp. 7183-90, 2004 (PubMed).

Li, Yang, Ashwell: "TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2." in: Nature, Vol. 416, Issue 6878, pp. 345-7, 2002 (PubMed).

Deveraux, Roy, Stennicke, Van Arsdale, Zhou, Srinivasula, Alnemri, Salvesen, Reed: "IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases." in: The EMBO journal, Vol. 17, Issue 8, pp. 2215-23, 1998 (PubMed).

Background publications Rothe, Pan, Henzel, Ayres, Goeddel: "The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins." in: Cell, Vol. 83, Issue 7, pp. 1243-52, 1996 (PubMed).