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  • 产品名称：BCL2-InteractingKiller(Apoptosis-Inducing)(BIK)Peptide

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  • 产品厂商：PromoCell
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简单介绍：
BCL2-InteractingKiller(Apoptosis-Inducing)(BIK)Peptide
详情介绍：
Blocked Antibody anti-BIK antibody (BCL2-Interacting Killer (Apoptosis-Inducing)) (ABIN1001872)
Characteristics 15 amino acids near the amino terminus of human Bik.
Research Area Apoptosis/Necrosis
Application Notes Bik peptide is used for blocking the activity of Bik antibody . It usually blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37ºC.
Restrictions For Research Use only
Format Liquid
Concentration 200 µg/mL
Buffer Supplied in PBS pH 7.2 (10 mM NaH₂PO₄, 10 mM Na₂HPO₄, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice For products with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. The peptide solution should be gently mixed before use.
Storage -20 °C
Storage Comment Store at -20°C, stable for one year.
Expiry Date 12 months
Background publications Kuwata, Watanabe, Jiang, Yamamoto, Tomiyama-Miyaji, Abo, Miyazaki, Naito: "AIM inhibits apoptosis of T cells and NKT cells in Corynebacterium-induced granuloma formation in mice." in: The American journal of pathology, Vol. 162, Issue 3, pp. 837-47, 2003 (PubMed).

Product cited in: Haruta, Kato, Hashimoto, Minjares, Kennedy, Uto, Yamauchi, Kobayashi, Yusa, Müller, Hayashi, Miyazaki: "Association of AIM, a novel apoptosis inhibitory factor, with hepatitis via supporting macrophage survival and enhancing phagocytotic function of macrophages." in: The Journal of biological chemistry, Vol. 276, Issue 25, pp. 22910-4, 2001 (PubMed).

Biancone, Bowen, Lim, Aruffo, Andres, Stamenkovic: "Identification of a novel inducible cell-surface ligand of CD5 on activated lymphocytes." in: The Journal of experimental medicine, Vol. 184, Issue 3, pp. 811-9, 1997 (PubMed).