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  • 产品名称：Caspase12(CASP12)(N-Term)Peptide

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  • 产品厂商：PromoCell
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简单介绍：
Caspase12(CASP12)(N-Term)Peptide
详情介绍：
Blocked Antibody anti-Caspase 12 (CASP12) (N-Term) antibody (ABIN1001997)
Characteristics 16 amino amino terminus of mouse Caspase-12.
Application Notes Caspase-12 peptide is used for blocking the antibody activity of caspase-12 antibody. It usually blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37ºC
Restrictions For Research Use only
Format Liquid
Concentration 200 µg/mL
Buffer Supplied in PBS pH 7.2 (10 mM NaH₂PO₄, 10 mM Na₂HPO₄, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice For products with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. The peptide solution should be gently mixed before use.
Storage -20 °C
Storage Comment Store at -20°C, stable for one year.
Expiry Date 12 months
Product cited in: Masumoto, Taniguchi, Nakayama, Ayukawa, Sagara: "Murine ortholog of ASC, a CARD-containing protein, self-associates and exhibits restricted distribution in developing mouse embryos." in: Experimental cell research, Vol. 262, Issue 2, pp. 128-33, 2001 (PubMed).

Conway, McConnell, Bowring, Donald, Warren, Vertino: "TMS1, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-induced gene silencing in human breast cancers." in: Cancer research, Vol. 60, Issue 22, pp. 6236-42, 2000 (PubMed).

Masumoto, Taniguchi, Ayukawa, Sarvotham, Kishino, Niikawa, Hidaka, Katsuyama, Higuchi, Sagara: "ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells." in: The Journal of biological chemistry, Vol. 274, Issue 48, pp. 33835-8, 1999 (PubMed).

Background publications McConnell, Vertino: "Activation of a caspase-9-mediated apoptotic pathway by subcellular redistribution of the novel caspase recruitment domain protein TMS1." in: Cancer research, Vol. 60, Issue 22, pp. 6243-7, 2000 (PubMed).