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  • 产品名称：BCL2-AssociatedAthanogene(BAG1)(N-Term)Peptide

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  • 产品厂商：PromoCell
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简单介绍：
BCL2-AssociatedAthanogene(BAG1)(N-Term)Peptide
详情介绍：
Blocked Antibody anti-Bcl-2 Binding Athanogene 1 (N-Term) antibody (ABIN1001871)
Characteristics 14 amino acids near the amino terminus of human BAG1.
Application Notes BAG-1 peptide is used for blocking the activity of BAG1 antibody . It usually blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37˚C.
Restrictions For Research Use only
Format Liquid
Concentration 200 µg/mL
Buffer Supplied in PBS pH 7.2 (10 mM NaH₂PO₄, 10 mM Na₂HPO₄, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice For products with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. The peptide solution should be gently mixed before use.
Storage -20 °C
Storage Comment Store at -20°C, stable for one year.
Expiry Date 12 months
Product cited in: Divanovic, Trompette, Atabani, Madan, Golenbock, Visintin, Finberg, Tarakhovsky, Vogel, Belkaid, Kurt-Jones, Karp: "Inhibition of TLR-4/MD-2 signaling by RP105/MD-1." in: Journal of endotoxin research, Vol. 11, Issue 6, pp. 363-8, 2005 (PubMed).

Nagai, Kobayashi, Motoi, Ishiguro, Akashi, Saitoh, Kusumoto, Kaisho, Akira, Matsumoto, Takatsu, Miyake: "The radioprotective 105/MD-1 complex links TLR2 and TLR4/MD-2 in antibody response to microbial membranes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 11, pp. 7043-9, 2005 (PubMed).

Tsuneyoshi, Fukudome, Kohara, Tomimasu, Gauchat, Nakatake, Kimoto: "The functional and structural properties of MD-2 required for lipopolysaccharide binding are absent in MD-1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 1, pp. 340-4, 2004 (PubMed).

Background publications Takeda, Kaisho, Akira: "Toll-like receptors." in: Annual review of immunology, Vol. 21, pp. 335-76, 2003 (PubMed).