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  • 产品名称：Caspase12(CASP12)(LargeIsoform)Peptide

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  • 产品厂商：PromoCell
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简单介绍：
Caspase12(CASP12)(LargeIsoform)Peptide
详情介绍：
Blocked Antibody anti-Caspase 12 (CASP12) (Large Isoform) antibody (ABIN1001999)
Characteristics 18 amino acids within the large cleavage product of murine caspase-12.
Application Notes Caspase-12 peptide is used for blocking the activity of the Caspase-12 (large) antibody . It usually blocks the antibody activity completely in Western blots by incubating the peptide with equal volume of antibody for 30 min at 37ºC.
Restrictions For Research Use only
Format Liquid
Concentration 200 µg/mL
Buffer Supplied in PBS pH 7.2 (10 mM NaH₂PO₄, 10 mM Na₂HPO₄, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice For products with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. The peptide solution should be gently mixed before use.
Storage -20 °C
Storage Comment Store at -20°C, stable for one year.
Expiry Date 12 months
Background publications Carson-Walter, Watkins, Nanda, Vogelstein, Kinzler, St Croix: "Cell surface tumor endothelial markers are conserved in mice and humans." in: Cancer research, Vol. 61, Issue 18, pp. 6649-55, 2001 (PubMed).

Bradley, Mogridge, Mourez, Collier, Young: "Identification of the cellular receptor for anthrax toxin." in: Nature, Vol. 414, Issue 6860, pp. 225-9, 2001 (PubMed).

Duesbery, Webb, Leppla, Gordon, Klimpel, Copeland, Ahn, Oskarsson, Fukasawa, Paull, Vande Woude: "Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor." in: Science (New York, N.Y.), Vol. 280, Issue 5364, pp. 734-7, 1998 (PubMed).

Molloy, Bresnahan, Leppla, Klimpel, Thomas: "Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen." in: The Journal of biological chemistry, Vol. 267, Issue 23, pp. 16396-402, 1992 (PubMed).