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  • 产品名称：CASP8andFADD-LikeApoptosisRegulator(CFLAR)(C-Term)Peptide

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  • 产品厂商：PromoCell
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简单介绍：
CASP8andFADD-LikeApoptosisRegulator(CFLAR)(C-Term)Peptide
详情介绍：
Blocked Antibody anti-FLICE Inhibitory Protein (CFLAR) (C-Term) antibody (ABIN1002319)
Characteristics 18 amino acids near the carboxy terminus of human FLIP.
Research Area Signaling, Apoptosis/Necrosis
Application Notes FLIP peptide is used for blocking the activity of Anti-FLIP . Incubating the peptide with equal volume of antibody for 30 min at 37ºC usually completely blocks the antibody activity in Western blotting.
Restrictions For Research Use only
Format Liquid
Concentration 200 µg/mL
Buffer Supplied in PBS pH 7.2 (10 mM NaH₂PO₄, 10 mM Na₂HPO₄, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice For products with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. The peptide solution should be gently mixed before use.
Storage -20 °C
Storage Comment Store at -20°C, stable for one year.
Expiry Date 12 months
Product cited in: Zhang, Zhou, Miller: "A splicing variant of a death domain protein that is regulated by a mitogen-activated kinase is a substrate for c-Jun N-terminal kinase in the human central nervous system." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 5, pp. 2586-91, 1998 (PubMed).

Schievella, Chen, Graham, Lin: "MADD, a novel death domain protein that interacts with the type 1 tumor necrosis factor receptor and activates mitogen-activated protein kinase." in: The Journal of biological chemistry, Vol. 272, Issue 18, pp. 12069-75, 1997 (PubMed).

Chow, Lee: "DENN, a novel human gene differentially expressed in normal and neoplastic cells." in: DNA sequence : the journal of DNA sequencing and mapping, Vol. 6, Issue 5, pp. 263-73, 1997 (PubMed).