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  • 产品名称：Chemokine(C-X-CMotif)Receptor4(CXCR4)(N-Term)Peptide

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  • 产品厂商：PromoCell
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简单介绍：
Chemokine(C-X-CMotif)Receptor4(CXCR4)(N-Term)Peptide
详情介绍：
Blocked Antibody anti-CX3C-Chemokine Receptor 4 (HIV Receptor) (N-Term) antibody (ABIN1002169)
Characteristics 14 amino amino terminus of human CXCR4.
Research Area Chemokines, Receptors
Application Notes CXCR4 peptide is used for blocking the activity of Anti-CXCR4 . Incubating the peptide with equal volume of antibody for 30 min at 37ºC usually completely blocks the activity of Anti-CXCR4 in Western blotting.
Restrictions For Research Use only
Format Liquid
Concentration 200 µg/mL
Buffer Supplied in PBS pH 7.2 (10 mM NaH₂PO₄, 10 mM Na₂HPO₄, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice For products with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. The peptide solution should be gently mixed before use.
Storage -20 °C
Storage Comment Store at -20°C, stable for one year.
Expiry Date 12 months
Background publications Dimitrov: "How do viruses enter cells? The HIV coreceptors teach us a lesson of complexity." in: Cell, Vol. 91, Issue 6, pp. 721-30, 1998 (PubMed).

Berson, Long, Doranz, Rucker, Jirik, Doms: "A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains." in: Journal of virology, Vol. 70, Issue 9, pp. 6288-95, 1996 (PubMed).

Feng, Broder, Kennedy, Berger: "HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor." in: Science (New York, N.Y.), Vol. 272, Issue 5263, pp. 872-7, 1996 (PubMed).

Doranz, Rucker, Yi, Smyth, Samson, Peiper, Parmentier, Collman, Doms: "A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors." in: Cell, Vol. 85, Issue 7, pp. 1149-58, 1996 (PubMed).