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  • 产品名称：CheckpointKinase2(CHEK2)(N-Term)Peptide

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  • 产品厂商：PromoCell
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简单介绍：
CheckpointKinase2(CHEK2)(N-Term)Peptide
详情介绍：
Blocked Antibody anti-Chk2 (Novel Check Point Kinase) (N-Term) antibody (ABIN1002139)
Characteristics 17 amino amino terminus of human Chk2.
Research Area Kinases/Phosphatases, Cell Cycle
Application Notes Chk2 peptide is used for blocking the antibody activity of Chk2 antibody. It usually blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37ºC
Restrictions For Research Use only
Format Liquid
Concentration 200 µg/mL
Buffer Supplied in PBS pH 7.2 (10 mM NaH₂PO₄, 10 mM Na₂HPO₄, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice For products with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. The peptide solution should be gently mixed before use.
Storage -20 °C
Storage Comment Store at -20°C, stable for one year.
Expiry Date 12 months
Product cited in: Pöhlmann, Baribaud, Lee, Leslie, Sanchez, Hiebenthal-Millow, Münch, Kirchhoff, Doms: "DC-SIGN interactions with human immunodeficiency virus type 1 and 2 and simian immunodeficiency virus." in: Journal of virology, Vol. 75, Issue 10, pp. 4664-72, 2001 (PubMed).

Soilleux, Barten, Trowsdale: "DC-SIGN; a related gene, DC-SIGNR; and CD23 form a cluster on 19p13." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 6, pp. 2937-42, 2000 (PubMed).

Geijtenbeek, Torensma, van Vliet, van Duijnhoven, Adema, van Kooyk, Figdor: "Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses." in: Cell, Vol. 100, Issue 5, pp. 575-85, 2000 (PubMed).

Background publications Geijtenbeek, Kwon, Torensma, van Vliet, van Duijnhoven, Middel, Cornelissen, Nottet, KewalRamani, Littman, Figdor, van Kooyk: "DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells." in: Cell, Vol. 100, Issue 5, pp. 587-97, 2000 (PubMed).