产品详情
  • 产品名称:TumorNecrosisFactor(Ligand)Superfamily,Member9(TNFSF9)(Active)protein(FcTag)

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  • 产品厂商:ACROBiosystems
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简单介绍:
TumorNecrosisFactor(Ligand)Superfamily,Member9(TNFSF9)(Active)protein(FcTag)
详情介绍:
Characteristics This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 49 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.
Purity >95 % as determined by SDS-PAGE.
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Background Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD). Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
Molecular Weight 49 kDa
NCBI Accession NP_033430
UniProt P41274
Pathways Activated T Cell Proliferation
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer 50 mM Tris, 100 mM Glycine, pH 7.5
Storage -20 °C
Supplier Images
Binding Studies (Bind) image for Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (Active) protein (Fc Tag) (ABIN2870709) Immobilized Mouse 4-1BB, His Tag (Cat# 41B-M52H7) at 0.5μg/mL (100 µl/well),can bind ...
SDS-PAGE (SDS) image for Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9) (Active) protein (Fc Tag) (ABIN2870709) Mouse 4-1BB Ligand , Fc Tag on SDS-PAGE under reducing (R) condition. The gel was sta...