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  • 产品名称：Glyceraldehyde-3-PhosphateDehydrogenase(GAPDH)(Active)protein(Histag)

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  • 产品厂商：ACROBiosystems
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简单介绍：
Glyceraldehyde-3-PhosphateDehydrogenase(GAPDH)(Active)protein(Histag)
详情介绍：
Characteristics This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 36.9 kDa. The protein migrates as 37 kDa under reducing (R) condition (SDS-PAGE).
Purity >95 % as determined by SDS-PAGE.
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Background Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is also known as Peptidyl-cysteine S-nitrosylase GAPDH, which is an enzyme that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules. GAPDH has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. GAPDH can participate in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Also, GAPDH can modulate the organization and assembly of the cytoskeleton. Furthermore, GAPDH is a component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes.
Molecular Weight 36.9 kDa
UniProt P04406
Research Area Cancer, Metabolism, Alzheimer's Disease, Enzymes
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer 50 mM Tris, 150 mM NaCl, pH 7.5
Storage -20 °C
Supplier Images
SDS-PAGE (SDS) image for Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (Active) protein (His tag) (ABIN2870641) Human GAPDH, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained ov...