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  • 产品名称：TransferrinReceptor(p90,CD71)(TFRC)(Active)protein(Biotin,Histag)

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  • 产品厂商：ACROBiosystems
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简单介绍：
TransferrinReceptor(p90,CD71)(TFRC)(Active)protein(Biotin,Histag)
详情介绍：
Brand MABSol®,UltraLys
Specificity The primary amines in the side chains of lysine residues and the N-terminus of the protein are conjugated with biotins using standard chemical labeling method. A standard biotin reagent (13.5 angstroms) is used in this product.
Characteristics This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 76 kDa. The protein migrates as 80-85 kDa on a SDS-PAGE gel under reducing (R) condition due to glycosylation.
Purity >92 % as determined by SDS-PAGE.
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Grade Ultra Sensitive
ProductDetails: Biological Activity Comment Measured by its binding ability in a functional ELISA. Immobilized Human Transferrin /TF Protein (Cat# TRN-H4229) at 10 μg/mL (100 μL/well), can bind Biotinylated Human CD71 Protein (Cat# TFR-H8243). The EC50 is typically 0. 04. 4 μg/mL.
Background CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukomia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.
Molecular Weight 76 kDa
UniProt P02786
Pathways Transition Metal Ion Homeostasis
Comment

A chemically labeled biotinylated protein with ultra sensitivity.
The product is produced using a chemical labeling approach. The primary amines in the side chains of lysine residues and the N-terminus of protein are conjugated with biotins.
Chemical labeling usually results in multiple biotin attachment on a single protein molecule, which could potentially lead to higher detection sensitivity.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer PBS, pH 7.4
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment Lyophilized Protein should be stored at -20 °C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20 °C or -70 °C. Avoid repeated freeze-thaw cycles.
Supplier Images
SDS-PAGE (SDS) image for Transferrin Receptor (p90, CD71) (TFRC) (Active) protein (Biotin,His tag) (ABIN2444223) Biotinylated Human Transferrin R on SDS-PAGE under reducing (R) condition. The gel wa...
Binding Studies (Bind) image for Transferrin Receptor (p90, CD71) (TFRC) (Active) protein (Biotin,His tag) (ABIN2444223) Immobilized Human Transferrin, His Tag (Cat# TRN-H4229) at 10 μg/mL (100 µL/well),can...