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  • 产品名称：PoliovirusReceptor(PVR)(AA21-343)(Active)protein(FcTag)

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  • 产品厂商：ACROBiosystems
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简单介绍：
PoliovirusReceptor(PVR)(AA21-343)(Active)protein(FcTag)
详情介绍：
Characteristics This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 62.2 kDa. As a result of glycosylation, The protein migrates as 70-100 kDa under reducing (R) condition and 130-160 kDa under non-reducing (NR) condition on SDS-PAGE gel.
Purity >95 % as determined by SDS-PAGE.
Endotoxin Level Less than 0.1 EU per μg by the LAL method.
Background CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that is encoded by the PVR gene. CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155's normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. The role of CD155 in the immune system is unclear, though it may be involved in intestinal humoral immune responses. Subsequent data has also suggested that CD155 may also be used to positively select MHC-independent T cells in the thymus.
Molecular Weight 62.2 kDa
NCBI Accession NP_006496
Pathways Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization
Restrictions For Research Use only
Format Lyophilized
Reconstitution For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer 50 mM tris, 100 mM glycine, pH 7.5
Storage -20 °C
Supplier Images
SDS-PAGE (SDS) image for Poliovirus Receptor (PVR) (AA 21-343) (Active) protein (Fc Tag) (ABIN4949085) Human CD155, mouse IgG2a Fc Tag on SDS-PAGE under reducing (R) and no-reducing (NR) c...
image for Poliovirus Receptor (PVR) (AA 21-343) (Active) protein (Fc Tag) (ABIN4949085) Measured by its binding ability in a functional ELISA. Immobilized Human DNAM-1, Fc T...
image for Poliovirus Receptor (PVR) (AA 21-343) (Active) protein (Fc Tag) (ABIN4949085) Measured by its binding ability in a functional ELISA. Immobilized Human TIGIT, Fc Ta...