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  • 产品名称：Lectin,Galactoside-Binding,Soluble,9(LGALS9)(AA2-323)(Active)protein(Histag)

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  • 产品厂商：ACROBiosystems
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简单介绍：
Lectin,Galactoside-Binding,Soluble,9(LGALS9)(AA2-323)(Active)protein(Histag)
详情介绍：
Characteristics This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 36.6 kDa. The protein migrates as 40-50 kDa under reducing (R) condition (SDS-PAGE).
Purity >95 % as determined by SDS-PAGE.
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Background Galectin-9 (LGALS9) is also known as tumor antigen HOM-HD-21 and ecalectin. Galectins are a family of proteins defined by their binding specificity for β-galactoside sugars, such as N-acetyllactosamine (Galβ1-3GlcNAc or Galβ1-4GlcNAc), which can be bound to proteins by either N-linked or O-linked glycosylation. As for Galectin-9, it has high affinity for the Forssman pentasaccharide, and it is also the ligand for HAVCR2/TIM3. Forthermore, Galectin-9 stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth.
Molecular Weight 36.6 kDa
NCBI Accession NP_002299
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer 20 mM MOPS, 50 mM NaCl, 1 mM EDTA, 2 mM DTT, pH 7.4
Storage -20 °C
Supplier Images
SDS-PAGE (SDS) image for Lectin, Galactoside-Binding, Soluble, 9 (LGALS9) (AA 2-323) (Active) protein (His tag) (ABIN4949099) Human Galectin-9, His Tag on SDS-PAGE under reducing (R) condition. The gel was stain...