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  • 产品名称：TumorNecrosisFactorReceptorSuperfamily,Member17(TNFRSF17)(AA1-54)(Active)protei

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  • 产品厂商：ACROBiosystems
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简单介绍：
TumorNecrosisFactorReceptorSuperfamily,Member17(TNFRSF17)(AA1-54)(Active)protein(FcTag,FITC)
详情介绍：
Characteristics This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 32 kDa. As a result of glycosylation, the protein migrates as 38-42 kDa under reducing (R) condition, and 60-70 kDa under non-reducing (NR) condition (SDS-PAGE).
Purity >92 % as determined by SDS-PAGE.
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Background Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.
Molecular Weight 32 kDa
UniProt Q02223
Research Area Growth Factors, Cancer
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer PBS, pH 7.4
Storage -20 °C
Supplier Images
SDS-PAGE (SDS) image for Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-54) (Active) protein (Fc Tag,FITC) (ABIN4949066) FITC-Labeled Human BCMA, Fc Tag on SDS-PAGE under reducing (R) and no-reducing (NR) c...
Binding Studies (Bind) image for Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) (AA 1-54) (Active) protein (Fc Tag,FITC) (ABIN4949066) Immobilized Human BAFF, Fc Tag with a linear range of 0.15-0.625 μg/mL.