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  • 产品名称：ProgrammedCellDeath1Ligand2(PDCD1LG2)(AA20-219)(Active)protein(FcTag)

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  • 产品厂商：ACROBiosystems
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简单介绍：
ProgrammedCellDeath1Ligand2(PDCD1LG2)(AA20-219)(Active)protein(FcTag)
详情介绍：
Characteristics This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 49.6 kDa. As a result of glycosylation, The protein migrates as 60-70 kDa under reducing (R) condition and 140 kDa under non-reducing (NR) condition on SDS-PAGE gel.
Purity >95 % as determined by SDS-PAGE.
Endotoxin Level Less than 0.1 EU per μg by the LAL method.
Background Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Molecular Weight 49.6 kDa
NCBI Accession NP_067371
UniProt Q9WUL5
Restrictions For Research Use only
Format Lyophilized
Reconstitution For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer PBS, pH 7.4
Storage -20 °C
Supplier Images
SDS-PAGE (SDS) image for Programmed Cell Death 1 Ligand 2 (PDCD1LG2) (AA 20-219) (Active) protein (Fc Tag) (ABIN4949188) Mouse PD-L2, mouse IgG2a Fc Tag, low endotoxin on SDS-PAGE under reducing (R) and no-...