产品详情
  • 产品名称:K-Cadherin(CDH6)(AA19-615)(Active)protein(Histag)

  • 产品型号:
  • 产品厂商:ACROBiosystems
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简单介绍:
K-Cadherin(CDH6)(AA19-615)(Active)protein(Histag)
详情介绍:
Characteristics This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 67.2 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity >90 % as determined by SDS-PAGE.
Sterility 0.22 μm filtered
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Background Cadherin-6 (CDH6) is also known as Kidney cadherin (K-cadherin or KCAD), is a a type II classical cadherin from the cadherin superfamily. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH6 / KCAD contains five cadherin domains. CDH6 is highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression and also expressed in certain liver and kidney carcinomas.
Molecular Weight 67.2 kDa
UniProt P55285
Research Area Extracellular Matrix, Signaling, Cytoskeleton
Pathways Cell-Cell Junction Organization
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer PBS, pH 7.4
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
Supplier Images
SDS-PAGE (SDS) image for K-Cadherin (CDH6) (AA 19-615) (Active) protein (His tag) (ABIN2180863) Human Cadherin-6, His Tag on SDS-PAGE under reducing (R) condition. The gel was stain...