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  • 产品名称：Glypican3(GPC3)(AA25-557)(Active)protein(FcTag)

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  • 产品厂商：ACROBiosystems
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简单介绍：
Glypican3(GPC3)(AA25-557)(Active)protein(FcTag)
详情介绍：
Characteristics This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 87.2 kDa. GP3-M5254 may be cleaved into secrete GPC3, short propeptide (aa ?-557) & Fc tag, long propeptide (aa 358-557 predicted) & Fc tag. The protein migrates as 100 kDa (secrete GPC3 & propeptide & Fc tag), 58 kDa (long propeptide & Fc tag), 40 kDa (short propeptide & Fc tag) and 35 kDa Human IgG1 Fc fragment on a SDS-PAGE gel under reducing (R) condition.
Purity 90 % GPC3 and 2-8 % human IgG1 Fc fragment as determined by SDS-PAGE.
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Background Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
Molecular Weight 87.2 kDa
NCBI Accession NP_057906
UniProt Q8CFZ4
Research Area Lineage Markers
Pathways Glycosaminoglycan Metabolic Process
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer 50 mM Tris, 100 mM Glycine, pH 7.5
Storage -20 °C
Supplier Images
image for Glypican 3 (GPC3) (AA 25-557) (Active) protein (Fc Tag) (ABIN4949172) Measured by its binding ability in a functional ELISA. Immobilized Human FGF basic, T...
SDS-PAGE (SDS) image for Glypican 3 (GPC3) (AA 25-557) (Active) protein (Fc Tag) (ABIN4949172) Mouse Glypican 3 / GPC3, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was...