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  • 产品名称：Hemagglutinin(HA)(AA19-521),(H7N9)(Active)protein(Histag)

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  • 产品厂商：ACROBiosystems
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简单介绍：
Hemagglutinin(HA)(AA19-521),(H7N9)(Active)protein(Histag)
详情介绍：
Characteristics This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 58.6 kDa. The protein migrates as 63-75 kDa under reducing (R) condition (SDS-PAGE).
Purity >95 % as determined by SDS-PAGE.
Sterility 0.22 μm filtered
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
ProductDetails: Biological Activity Comment Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized Influenza HA,c-His Protein (HA9-V5227) at 2 μg/mL can bind Anti-Influenza HA MAb CM2S3 (CR1-M2S3) with a linear range of 0.5-20 μg/mL when use a secondary antibody HRP*-Goat anti Human IgG, Fcγ Fragment Specific,1:5000 from Jackson.
Background Influenza, commonly known as "the flu", is an infectious disease of birds and mammals caused by RNA viruses of the family Orthomyxoviridae, the influenza viruses. The virus is divided into three main types (Influenzavirus A, Influenzavirus B, and Influenzavirus C), which are distinguished by differences in two major internal proteins (hemagglutinin (HA) and neuraminidase (NA), which are the most important targets for the immune system. The type A viruses are the most virulent human pathogens among the three influenza types and cause the most severe disease. The serotypes that have been confirmed in humans, ordered by the number of known human pandemic deaths, are: H1N1, H2N2, H3N2, H5N1, H7N7, H1N2, H9N2, H7N2, H7N3, H10N7, H7N9. H7N9 is a serotype of the species Influenzavirus A (avian influenza virus or bird flu virus). H7 normally circulates amongst avian populations with some variants known to occasionally infect humans. An H7N9 virus was first reported to have infected humans in 2013 in China.
Molecular Weight 58.6 kDa
Gene ID 18, 17
UniProt R4NN21
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer PBS, pH 7.4
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
Supplier Images
SDS-PAGE (SDS) image for Hemagglutinin (HA) (AA 19-521), (H7N9) (Active) protein (His tag) (ABIN2181202) Influenza A [A/Shanghai/2/2013(H7N9)] HA on SDS-PAGE under reducing (R) condition. Th...