产品详情
  • 产品名称:HEK-293CellsIgGisotypecontrol(Histag)

  • 产品型号:
  • 产品厂商:ACROBiosystems
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简单介绍:
HEK-293CellsIgGisotypecontrol(Histag)
详情介绍:
Isotype IgG
Fragment Fc fragment
Characteristics This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27 kDa. The protein migrates as 34 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity >95 % as determined by SDS-PAGE.
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Background Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
Molecular Weight 27 kDa
UniProt P01857
Research Area Secondary Antibodies
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer 50 mM Tris, 100 mM Glycine, pH 7.5
Storage -20 °C
Supplier Images
SDS-PAGE (SDS) image for HEK-293 Cells IgG isotype control (His tag) (ABIN2870651) Human IgG1 Fc, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained ...