产品详情
查看大图

  • 产品名称：butyrophilin,Subfamily3,MemberA3(BTN3A3)(AA30-248)(Active)protein(Histag)

  • 产品型号：
  • 产品厂商：ACROBiosystems
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
butyrophilin,Subfamily3,MemberA3(BTN3A3)(AA30-248)(Active)protein(Histag)
详情介绍：
Characteristics This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.5 kDa. The protein migrates as 28 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity >95 % as determined by SDS-PAGE.
Sterility 0.22 μm filtered
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Background Butyrophilin subfamily 3 member A3 (BTN3A3),a member of the immunoglobulin superfamily and BTN/MOG family, is also known as BTF3, which contains one B30.2/SPRY domain and two Ig-like V-type (immunoglobulin-like) domains. BTN3A3 is detected in peripheral blood mononuclear cells ,T-cells ,spleen and lymphocytes. BTN3A3 also plays a role in T-cell responses in the adaptive immune response. Stimulation of human butyrophilin 3(BTN3) molecules results in negative regulation of cellular immunity.
Molecular Weight 25.5 kDa
Research Area Cardiovascular
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer PBS, pH 7.4
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
Supplier Images
SDS-PAGE (SDS) image for butyrophilin, Subfamily 3, Member A3 (BTN3A3) (AA 30-248) (Active) protein (His tag) (ABIN2180657) Human BTN3A3, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained o...
Background publications Palakodeti, Sandstrom, Sundaresan, Harly, Nedellec, Olive, Scotet, Bonneville, Adams: "The molecular basis for modulation of human V?9V?2 T cell responses by CD277/butyrophilin-3 (BTN3A)-specific antibodies." in: The Journal of biological chemistry, Vol. 287, Issue 39, pp. 32780-90, 2012 (PubMed).

Yamashiro, Yoshizaki, Tadaki, Egawa, Seo: "Stimulation of human butyrophilin 3 molecules results in negative regulation of cellular immunity." in: Journal of leukocyte biology, Vol. 88, Issue 4, pp. 757-67, 2010 (PubMed).