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  • 产品名称：Dipeptidyl-Peptidase7(DPP7)(AA22-492)(Active)protein(Histag)

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  • 产品厂商：ACROBiosystems
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简单介绍：
Dipeptidyl-Peptidase7(DPP7)(AA22-492)(Active)protein(Histag)
详情介绍：
Characteristics This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 53 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity >95 % as determined by SDS-PAGE.
Sterility 0.22 μm filtered
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
ProductDetails: Biological Activity Comment Biological Activity: Measured by its ability to cleave the fluorogenic peptide substrate, Lys-Pro-AMC (KP-AMC). The specific activity is >4000 pmol/min/μg.
Background Dipeptidyl peptidase 2 (DPP2 or DPP II) is also known as Dipeptidyl peptidase 7 (DPP7), Quiescent cell proline dipeptidase (QPP), which belongs to the peptidase S28 family. DPP7 / DPP2 is detected in seminal plasma (at protein level). When the pH is 5.5, Dipeptidyl peptidase 2 display a optimum catalytic activity. DPP7 has low activity at pH 7 and is inactive at pH 8. DPP7 plays an important role in the degradation of some oligopeptides.
Molecular Weight 53 kDa
UniProt Q9UHL4
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer 50 mM Tris, 150 mM NaCl, pH 7.5
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
Supplier Images
SDS-PAGE (SDS) image for Dipeptidyl-Peptidase 7 (DPP7) (AA 22-492) (Active) protein (His tag) (ABIN2180986) Human DPPII, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained ov...
Background publications Maes, Lambeir, Gilany, Senten, Van der Veken, Leiting, Augustyns, Scharpé, De Meester et al.: "Kinetic investigation of human dipeptidyl peptidase II (DPPII)-mediated hydrolysis of dipeptide derivatives and its identification as quiescent cell proline dipeptidase (QPP)/dipeptidyl peptidase 7 ..." in: The Biochemical journal, Vol. 386, Issue Pt 2, pp. 315-24, 2005 (PubMed).