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  • 产品名称：OligodendrocyteMyelinGlycoprotein(OMG)(AA25-420)(Active)protein(Histag)

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  • 产品厂商：ACROBiosystems
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简单介绍：
OligodendrocyteMyelinGlycoprotein(OMG)(AA25-420)(Active)protein(Histag)
详情介绍：
Characteristics This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 45.5 kDa. The protein migrates as 90-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity >92 % as determined by SDS-PAGE.
Sterility 0.22 μm filtered
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Background Oligodendrocyte-myelin glycoprotein (OMG or OMGP), is a cell membrane protein which contains eight LRR (leucine-rich) repeats and one LRRNT domain. OMG / OMGP is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes in the central nervous system (CNS). OMG / OMGP play roles in both the developing and ***** central nervous system. OMG / OMGP may also be involved in the formation and maintenance of myelin sheaths.
Molecular Weight 45.5 kDa
UniProt P23515
Pathways Neurotrophin Signaling Pathway, Regulation of Cell Size
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer PBS, pH 7.4
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
Supplier Images
SDS-PAGE (SDS) image for Oligodendrocyte Myelin Glycoprotein (OMG) (AA 25-420) (Active) protein (His tag) (ABIN2181563) Human OMgp, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained ove...
Background publications Mikol, Gulcher, Stefansson: "The oligodendrocyte-myelin glycoprotein belongs to a distinct family of proteins and contains the HNK-1 carbohydrate." in: The Journal of cell biology, Vol. 110, Issue 2, pp. 471-9, 1990 (PubMed).

Mikol, Stefansson: "A phosphatidylinositol-linked peanut agglutinin-binding glycoprotein in central nervous system myelin and on oligodendrocytes." in: The Journal of cell biology, Vol. 106, Issue 4, pp. 1273-9, 1988 (PubMed).