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  • 产品名称：FattyAcidBindingProtein6,Ileal(FABP6)(AA2-128)(Active)protein(Histag)

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  • 产品厂商：ACROBiosystems
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简单介绍：
FattyAcidBindingProtein6,Ileal(FABP6)(AA2-128)(Active)protein(Histag)
详情介绍：
Characteristics This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 15.3 kDa. The protein migrates as 15 kDa under reducing (R) condition (SDS-PAGE).
Purity >92 % as determined by SDS-PAGE.
Sterility 0.22 μm filtered
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Background Fatty acid-binding protein 6 (FABP6), is also known as Intestinal bile acid-binding protein (I-BABP), Ileal lipid-binding protein (ILBP), Intestinal 15 kDa protein (I-15P), Gastrotropin (GT). FABP6 is a cytoplasm protein which belongs to the calycin superfamily and fatty-acid binding protein (FABP) family. Isoform 2 of FABP6 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform 1 of FABP6 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Ileal protein FABP6 stimulates gastric acid and pepsinogen secretion. FABP6 seems to be able to bind to bile salts and bilirubins. Isoform 2 of FABP6 is essential for the survival of colon cancer cells to bile acid-induced apoptosis.
Molecular Weight 15.3 kDa
UniProt P51161
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer PBS, pH 7.4
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
Supplier Images
SDS-PAGE (SDS) image for Fatty Acid Binding Protein 6, Ileal (FABP6) (AA 2-128) (Active) protein (His tag) (ABIN2181058) Human FABP6, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained ov...
Background publications Fang, Dean, Smith: "A novel variant of ileal bile acid binding protein is up-regulated through nuclear factor-kappaB activation in colorectal adenocarcinoma." in: Cancer research, Vol. 67, Issue 19, pp. 9039-46, 2007 (PubMed).

Fujita, Fujii, Kanda, Sato, Hatakeyama, Ono: "Molecular cloning, expression, and characterization of a human intestinal 15-kDa protein." in: European journal of biochemistry / FEBS, Vol. 233, Issue 2, pp. 406-13, 1995 (PubMed).