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  • 产品名称：CD72Molecule(CD72)(AA117-359)(Active)protein(FcTag)

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  • 产品厂商：ACROBiosystems
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简单介绍：
CD72Molecule(CD72)(AA117-359)(Active)protein(FcTag)
详情介绍：
Characteristics This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 54 kDa. The protein migrates as 60-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity >95 % as determined by SDS-PAGE.
Sterility 0.22 μm filtered
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Background B-cell differentiation antigen CD72 is also known as Lyb-2. CD72 contains one C-type lectin domain. CD72 is a protein active in the immune system of animals. CD72 consists of two identical halves, each of about 39-43 kD, and is a C-type lectin. Its primarily locus of expression is B-cells, where it appears to mediate aspects of B-cell - T-cell interaction. CD72 plays a role in B-cell proliferation and differentiation. CD72 is a ligand for CD5.
Molecular Weight 54 kDa
UniProt P21854
Research Area Stem Cells, Hematopoietic Progenitors, Adaptive Immunity, CD Antigens, Surface Receptors of Immune Cells
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer 50 mM Tris, 100 mM Glycine, pH 7.5
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
Supplier Images
SDS-PAGE (SDS) image for CD72 Molecule (CD72) (AA 117-359) (Active) protein (Fc Tag) (ABIN2180833) Human CD72, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained over...
Background publications von Hoegen, Waller: "Safety of human albumin based on spontaneously reported serious adverse events." in: Critical care medicine, Vol. 29, Issue 5, pp. 994-6, 2001 (PubMed).

Von Hoegen, Nakayama, Parnes: "Identification of a human protein homologous to the mouse Lyb-2 B cell differentiation antigen and sequence of the corresponding cDNA." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 144, Issue 12, pp. 4870-7, 1990 (PubMed).