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  • 产品名称：Mouseanti-ChickenIgAAntibody(FITC)

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  • 产品厂商：Acris-antibodies
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简单介绍：
Mouseanti-ChickenIgAAntibody(FITC)
详情介绍：
Clone A-1
Isotype IgG2b
Background Human IgA (immunoglobulin A) is a glycosylated protein of 160 kDa and is produced as a monomer or as a J chain linked dimer. Monomeric IgA constitutes 5-15 % of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces such as saliva, gastrointestinal secretion, bronchial fluids and milk. Mucosal IgA plays a major role in host defence by neutralising infectious agents at mucosal surfaces. The production is usually local and antigen specific IgA producing B cells can be found in regions under the lamina propria where they mature into dimeric IgA producing plasma cells. IgA deficiency is the most common immunodeficiency that may affect both serum and mucosal produced IgA.Synonyms: Chicken Immunoglobulin A
Molecular Weight 160 kDa
Research Area Immunology, Secondary Antibodies
Application Notes Flow Cytometry: < / = 1 μg/10^6 cells. Immunofluorescence.

Other applications not tested.
Otimal dilutions are dependent on conditions and should be determined by the user.
Comment

Excitation/Emission wavelength: 494 nm/514 nm
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS containing 0.09 % Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid repeated freezing and thawing.
This product is photosensitive and should be protected from light.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -28 °C for longer.
Background publications Chen, Lehmeyer, Cooper: "Evidence for an IgD homologue on chicken lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 129, Issue 6, pp. 2580-5, 1983 (PubMed).