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  • 产品名称：anti-SIRPAantibody(Signal-RegulatoryProteinalpha)(FITC)

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  • 产品厂商：Acris-antibodies
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简单介绍：
anti-SIRPAantibody(Signal-RegulatoryProteinalpha)(FITC)
详情介绍：
Immunogen Rat peritoneal macrophages. Spleen cells from immunised BALB/c mice were fused with the NSO/U mouse myeloma cell line.
Clone OX-41
Isotype IgG2a
Specificity This antibody recognises rat CD172a, also known as Signal regulatory protein (SIRP). MRC OX-41 binds to a different epitope on SIRP than ED9.
Purification Affinity chromatography on Protein G
Alternative Name CD172a / SIRPA (SIRPA Antibody Abstract)
Background CD172a is expressed selectively by myeloid cells and by neurons.Synonyms: BIT, Brain Ig-like molecule with tyrosine-based activation motifs, CD172 antigen-like family member A, Inhibitory receptor SHPS-1, MFR, MYD1, Macrophage fusion receptor, MyD-1 antigen, PTPNS1, SHP substrate 1, SHPS-1, SHPS1, Signal-regulatory protein alpha-1, Sirp-alpha-2, Sirp-alpha-3, Tyrosine-protein phosphatase non-receptor type substrate 1, p84
Gene ID 25528
NCBI Accession NP_037148
UniProt P97710
Research Area CD Antigens, Surface Receptors of Immune Cells, Signaling, Extracellular Matrix
Application Notes Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.1 mg/mL
Buffer PBS, pH 7.4 containing 0.09 % Sodium Azide and 1.0 % Bovine Serum Albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Adams, van der Laan, Vernon-Wilson, Renardel de Lavalette, Döpp, Dijkstra, Simmons, van den Berg: "Signal-regulatory protein is selectively expressed by myeloid and neuronal cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 4, pp. 1853-9, 1998 (PubMed).

Robinson, White, Mason: "Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognizing complement receptor type 3." in: Immunology, Vol. 57, Issue 2, pp. 239-47, 1986 (PubMed).

Barclay: "The localization of populations of lymphocytes defined by monoclonal antibodies in rat lymphoid tissues." in: Immunology, Vol. 42, Issue 4, pp. 593-600, 1981 (PubMed).