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  • 产品名称：anti-CD90antibody(THY1)(FITC)

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简单介绍：
anti-CD90antibody(THY1)(FITC)
详情介绍：
Clone 30-H12
Isotype IgG2b
Specificity This antibody recognises CD90.2/Thy-1.2 alloantigen (Mr. 18 kDa).
Characteristics Synonyms: Thy1.2, Thy-1.2, CD90, Thy-1, Thy-1 membrane glycoprotein
Alternative Name CD90 (THY1 Antibody Abstract)
Background CD90/Thy-1 is a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily, consisting of a single V-set domain. (Ref.1-3) The Thy-1.2 alloantigen is expressed on all thymocytes, peripheral T lymphocytes, and some intraepithelial T cells of most mouse strains. It is also expressed in the brain and at varying levels on other non-lymphoid tissues. The 30-H12 monoclonal antibody does not cross react with Mouse and Rat strains bearing the Thy-1.1 alloantigen (e.g., AKR/J,PL). (Ref.2-5).Synonyms: CD90, Thy-1, Thy-1 membrane glycoprotein, Thy-1.2, Thy1.2
Gene ID 21838
UniProt P01831
Research Area CD Antigens, Surface Receptors of Immune Cells, Experimental Models
Pathways Cell-Cell Junction Organization
Application Notes Flow Cytometry: < / = 1 μg/10^6 cells. (Ref.4,5)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS containing 0.09 % Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months
Supplier Images
Flow Cytometry (FACS) image for anti-CD90 antibody (THY1) (FITC) (ABIN371031) anti-CD90 (THY1) antibody (FITC)
Background publications Homans, Ferguson, Dwek, Rademacher, Anand, Williams: "Complete structure of the glycosyl phosphatidylinositol membrane anchor of rat brain Thy-1 glycoprotein." in: Nature, Vol. 333, Issue 6170, pp. 269-72, 1988 (PubMed).

Williams, Gagnon: "Neuronal cell Thy-1 glycoprotein: homology with immunoglobulin." in: Science (New York, N.Y.), Vol. 216, Issue 4547, pp. 696-703, 1982 (PubMed).

Ledbetter, Rouse, Micklem, Herzenberg: "T cell subsets defined by expression of Lyt-1,2,3 and Thy-1 antigens. Two-parameter immunofluorescence and cytotoxicity analysis with monoclonal antibodies modifies current views." in: The Journal of experimental medicine, Vol. 152, Issue 2, pp. 280-95, 1980 (PubMed).

Ledbetter, Herzenberg: "Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens." in: Immunological reviews, Vol. 47, pp. 63-90, 1980 (PubMed).