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  • 产品名称：anti-CD9antibody(CD9)(PE)

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简单介绍：
anti-CD9antibody(CD9)(PE)
详情介绍：
Immunogen Human platelet membrane. Spleen cells from immunised BALB/c mice were fused with cells from the SP2/0 mouse myeloma line.
Clone MM2-57
Isotype IgG2b
Purification Affinity chromatography on Protein A
Alternative Name CD9 (CD9 Antibody Abstract)
Background CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. It belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). It also regulates cell motility in a variety of cell lines, and appears to be an important regulator of Schwann cell behaviour in peripheral nerve.Synonyms: 5H9 antigen, Cell growth-inhibiting gene 2 protein, GIG2, Leukocyte antigen MIC3, MIC3, Motility-related protein, TSPAN29, Tetraspanin-29, p24
Gene ID 928
NCBI Accession NP_001760
UniProt P21926
Research Area Embryogenesis, Embryonic stem cells, Reproduction, CD Antigens, Surface Receptors of Immune Cells
Pathways Response to Water Deprivation, Cell-Cell Junction Organization
Application Notes Flow Cytometry: Use 10 μL of Neat-1/2 diluted antibody to label 10^6 cells or 100 μL whole blood.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Reconstitution Restore with distilled water.
Buffer PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice This product is photosensitive and should be protected from light
Storage 4 °C
Storage Comment Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE!
Background publications Boucheix, Benoit, Frachet, Billard, Worthington, Gagnon, Uzan: "Molecular cloning of the CD9 antigen. A new family of cell surface proteins." in: The Journal of biological chemistry, Vol. 266, Issue 1, pp. 117-22, 1991 (PubMed).