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  • 产品名称：anti-EMR3antibody(Egf-LikeModuleContaining,Mucin-Like,HormoneReceptor-Like3)(AA

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  • 产品厂商：Acris-antibodies
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简单介绍：
anti-EMR3antibody(Egf-LikeModuleContaining,Mucin-Like,HormoneReceptor-Like3)(AA3-97)(PE)
详情介绍：
Immunogen ARHO-EMR3-CD97 (EGF1) transfectants. Spleen cells from immunised Armenian hamsterwere fused with cells of the mouse SP2/0 myeloma cell line. Genename: EMR3
Clone 3D7
Isotype IgG
Specificity This antibody recognises epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 (EMR3), which is a 56 kDa member of the EGF-7 transmembrane (TM7) family of adhesion receptors.
Characteristics Synonyms: EGF-Like Module-Containing Mucin-Like Receptor 3, EMR-3, EGF-like module containingmucin-like hormone receptor-like 3
Purification Affinity chromatography on Protein G
Alternative Name EMR3 (EMR3 Antibody Abstract)
Background EMR3 is expressed at the cell surface as a heterodimer. The molecule is predominantly expressed on granulocytes, and at lower levels on mature myeloid cells, monocytes and dendritic cells. EMR3 is absent on lymphocytes, haematopoietic stem cells and myeloid progenitors. Studies suggest that the EMR3 Molecule is up-regulated during late stages of neutrophil differentiation and is a marker for terminally differentiated cells. The exact functions of EMR3 and its ligands have not yet been determined.Synonyms: EGF-like module receptor 3, EGF-like module-containing mucin-like hormone receptor-like 3
Gene ID 84658
UniProt Q9BY15
Research Area Signaling, Innate Immunity
Application Notes Flow cytometry (Neat - 1/5): use 10 μL of the suggested working dilution to label 10^6 cellsin 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Reconstitution Restore with 1.0 mL distilled water.
Concentration 0.1 mg/mL
Buffer PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month. This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.
Expiry Date 12 months
Background publications Stacey, Lin, Hilyard, Gordon, McKnight: "Human epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 is a new member of the EGF-TM7 family that recognizes a ligand on human macrophages and activated neutrophils." in: The Journal of biological chemistry, Vol. 276, Issue 22, pp. 18863-70, 2001 (PubMed).