产品详情
所在位置: 首页> 产品目录> 一抗>
查看大图

  • 产品名称：anti-IGF1Rantibody(Insulin-LikeGrowthFactor1Receptor)(C-Term)(Biotin)

  • 产品型号：
  • 产品厂商：Acris-antibodies
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
anti-IGF1Rantibody(Insulin-LikeGrowthFactor1Receptor)(C-Term)(Biotin)
详情介绍：
Immunogen Synthetic peptide conjugated to KLH. Remarks: Mol. Weight: 97 kDa
Clone 7G11
Isotype IgG1
Specificity This antibody specifically recognizes the C-terminus of IGF1 Receptor.
Characteristics Synonyms: IGF-I receptor, IGF1 Receptor, Insulin-like growth factor 1 receptor
Purification Subsequent Thiophilic Adsorption and Size Exclusion Chromatography
Components incl. positive Control
Alternative Name CD221 / IGF1R (IGF1R Antibody Abstract)
Background The IGF1 receptor (IGF1R) is a heterodimeric receptor tyrosine kinase with an extracellular alpha-chain, a transmembrane domain and an intracellular beta-chain. The IGF1 receptor is activated upon binding of the peptide hormones IGF1 and 2, leading to autophosphorylation of tyrosine residue 1131, 1135, and 1136 in the activation loop of the beta-chain. Additional autophosphorylation sites such as tyrosine residue 950 and 1316 regulate the assembly of signal transduction complexes.Synonyms: IGF-I receptor, IGF1 Receptor, Insulin-like growth factor 1 receptor
Molecular Weight 97 kDa
Gene ID 3480
UniProt P08069
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways RTK Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
Application Notes Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. Positive Control: Cell lysate from untreated A431 cells (See Protocols for more details).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Protocol Positive Control Cell Lysate A431 Untreated
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS, 0.09 % Sodium Azide, PEG and Sucrose
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-80 °C
Storage Comment Store the antibody (aliquote in liquid nitrogen) at -80 °C. Avoid repeated freezing and thawing. Thaw aliquots at 37 °C. Thawed aliquots may be stored at 4 °C up to 3 months.
Shelf life: one year from despatch.
Expiry Date 12 months