产品详情
所在位置: 首页> 产品目录> 一抗>
查看大图

  • 产品名称：anti-MHCClassII(I-AK,b,d,q,r)antibody(FITC)

  • 产品型号：
  • 产品厂商：Acris-antibodies
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
anti-MHCClassII(I-AK,b,d,q,r)antibody(FITC)
详情介绍：
Immunogen Murine thymic reticulum. Remarks: Antigen / Epitope: MHC Class II antigens are heterodimers consisting of one alpha-chain (31-34 kDa) and one beta-chain (26-29 kDa). The epitope has not been further characterized.
Clone ER-TR3
Isotype IgG2b
No Cross-Reactivity Human
Cross-Reactivity (Details) Species reactivity (tested):Mouse (Cells expressing MHC class II antigens.
Purification Affinity Chromatography.
Background MHC Class II antigens are heterodimers consisting of one alpha chain (31-34kD) and one beta chain (26-29kD). The family of monoclonal antibodies (ER-TR 3, ER-TR 2, ER-TR 1) detect MHC class II antigens encoded by the murine Ia region of the H-2 complex, corresponding to the human HLA-DR region. MHC Class II antigens are a valuable tool for studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these antibodies also stain stromal cells in the thymus. MHC Class II antigens are also inducible on a number of other cells (endothelium and epithelial cells) by interferon gamma.
Research Area Major Histocompatibility Complex (MHC), Immunology
Application Notes Flow Cytometry: 10 μg/mL (Use 10 μL of 1/10 diluted antibody to label 10^6 cells). Suggested Positive Control: mouse spleen. Has beed described to work in FACS.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.1 mg/mL
Buffer Phosphate buffered saline pH 7.2 (PBS) containing 10 mg/mL BSA as a stabilizer and 0.09 % Sodium Azide as a preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.
Supplier Images
image for anti-MHC Class II (I-A K,b,d,q,r) antibody (FITC) (ABIN111989) Distribution of ER-TR 1, ER-TR 2 and ER-TR 3 among mouse strains with independent and...
Background publications Van Vliet, Jenkinson, Kingston, Owen, Van Ewijk: "Stromal cell types in the developing thymus of the normal and nude mouse embryo." in: European journal of immunology, Vol. 15, Issue 7, pp. 675-81, 1985 (PubMed).

Van Vliet, Melis, Van Ewijk: "Monoclonal antibodies to stromal cell types of the mouse thymus." in: European journal of immunology, Vol. 14, Issue 6, pp. 524-9, 1984 (PubMed).