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  • 产品名称：anti-TNFSF9antibody(TumorNecrosisFactor(Ligand)Superfamily,Member9)(PE)

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  • 产品厂商：Acris-antibodies
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简单介绍：
anti-TNFSF9antibody(TumorNecrosisFactor(Ligand)Superfamily,Member9)(PE)
详情介绍：
Immunogen 41BBL-Fc Fusion Protein.
Clone AT113-2
Isotype IgG1
Specificity This antibody recognises murine 4-1BB Ligand (CD137L).
Purification Affinity chromatography on Protein G
Alternative Name 4-1BBL / TNFSF9 (TNFSF9 Antibody Abstract)
Background CD137L is a 50kD type 2 transmembrane protein, which is a member of the TNF superfamily. In mice CD137L is expressed on activated T-cells, B-cells, macrophages and dendritic cells. Interaction of CD137L with its receptor 4-1BB (CD137) is reported to be involved in T and B cell growth and T cell effector function.Synonyms: 4-1BB ligand, CD137L, Tumor necrosis factor ligand superfamily member 9
Gene ID 21950
NCBI Accession NP_033430
UniProt P41274
Pathways Activated T Cell Proliferation
Application Notes Flow Cytometry: The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Reconstitution Restore with 1 mL distilled water
Concentration 0.1 mg/mL
Buffer PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice This product is photosensitive and should be protected from light
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Background publications Goodwin, Din, Davis-Smith, Anderson, Gimpel, Sato, Maliszewski, Brannan, Copeland, Jenkins: "Molecular cloning of a ligand for the inducible T cell gene 4-1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor." in: European journal of immunology, Vol. 23, Issue 10, pp. 2631-41, 1993 (PubMed).