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  • 产品名称：anti-C5AR1antibody(ComplementComponent5aReceptor1)(AA1-31)(FITC)

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  • 产品厂商：Acris-antibodies
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简单介绍：
anti-C5AR1antibody(ComplementComponent5aReceptor1)(AA1-31)(FITC)
详情介绍：
Immunogen C5aR - peptide: Met1 - Asn31
Clone P12-1
Isotype IgG2a
Specificity The antibody recognizes the N-terminal extracellular segment of the human CD88 cell surface antigen (C5aR).
Purification Ion exchange chromatography
Alternative Name CD88 / C5R1 (C5AR1 Antibody Abstract)
Background CD88 is expressed by peripheral blood granulocytes and monocytes. Binding of C5a to CD88 leads to cellular activation, including chemotaxis.Synonyms: C5AR1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR, Complement Component 5a Receptor 1
Gene ID 728
NCBI Accession NP_001727
UniProt P21730
Application Notes Flow cytometry (use 10 μL of neat antibody solution to label 10^6 cells in 100 μL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.1 mg/mL
Handling Advice Dilute only prior to immediate use
Storage 4 °C
Storage Comment Store the antibody (undiluted) at 2-8 °C. DO NOT FREEZE! Freezing alkaline phosphatase conjugates will result in a substantial loss of enzymatic activity.
Supplier Images
Flow Cytometry (FACS) image for anti-C5AR1 antibody (Complement Component 5a Receptor 1) (AA 1-31) (FITC) (ABIN119310) Staining of human peripheral blood granulocytes with Mouse anti Human CD88-FITC
Background publications Elias, Reinhardt, Hautmann, Harms, Oppermann, Schroeter, Hellenbrand, Oster, Kurzai, Taha, Nossal, Frosch, Vogel: "[3rd Workshop on Epidemiology, Prevention and Treatment of Invasive Meningococcal Disease in Würzburg 2006]" in: Gesundheitswesen (Bundesverband der Ärzte des Öffentlichen Gesundheitsdienstes (Germany)), Vol. 69, Issue 4, pp. 256-62, 2007 (PubMed).

Hoopmann, Hehl, Neisel, Werfel: "[Associations between bioaerosols coming from livestock facilities and asthmatic symptoms in children]" in: Gesundheitswesen (Bundesverband der Ärzte des Öffentlichen Gesundheitsdienstes (Germany)), Vol. 68, Issue 8-9, pp. 575-84, 2006 (PubMed).

Oppermann, Götze: "Plasma clearance of the human C5a anaphylatoxin by binding to leucocyte C5a receptors." in: Immunology, Vol. 82, Issue 4, pp. 516-21, 1995 (PubMed).