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  • 产品名称：anti-MacrophageMannoseReceptor1antibody(MannoseReceptor,CType1)(Biotin)

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  • 产品厂商：Acris-antibodies
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简单介绍：
anti-MacrophageMannoseReceptor1antibody(MannoseReceptor,CType1)(Biotin)
详情介绍：
Immunogen Chimaeric CRD4-7-Fc protein. Spleen cells from immunised Fischer rats were fused with cells of the Y3 myeloma cell line.
Clone MR5D3
Isotype IgG2a
Specificity This antibody recognises the mannose receptor, a 175 kDa type 1 membrane protein that is also known as CD206. Clone MR5D3 has been reported to be non-inhibitory for the binding of the mannose receptor to carbohydrate ligands.
Purification Affinity chromatography on Protein G
Alternative Name CD206 / MRC1 (MRC1 Antibody Abstract)
Background CD206 is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia.Synonyms: C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, CLEC13D, CLEC13DL, MRC1L1, Macrophage mannose receptor, Macrophage mannose receptor 1-like protein 1
Gene ID 17533
NCBI Accession NP_032651
UniProt Q61830
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes Flow Cytometry: Neat - 1/10, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL, The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.1 mg/mL
Buffer PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Martinez-Pomares, Reid, Brown, Taylor, Stillion, Linehan, Zamze, Gordon, Wong: "Analysis of mannose receptor regulation by IL-4, IL-10, and proteolytic processing using novel monoclonal antibodies." in: Journal of leukocyte biology, Vol. 73, Issue 5, pp. 604-13, 2003 (PubMed).

Zamze, Martinez-Pomares, Jones, Taylor, Stillion, Gordon, Wong: "Recognition of bacterial capsular polysaccharides and lipopolysaccharides by the macrophage mannose receptor." in: The Journal of biological chemistry, Vol. 277, Issue 44, pp. 41613-23, 2002 (PubMed).