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  • 产品名称：anti-Integrinalpha2(ITGA2)antibody(Biotin)

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  • 产品厂商：Acris-antibodies
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简单介绍：
anti-Integrinalpha2(ITGA2)antibody(Biotin)
详情介绍：
Immunogen Spleen cells from immunised mice were fused with cells of the mouse NS1 myeloma cell line.
Clone AK7
Isotype IgG1
Specificity This antibody recognises the integrin alpha 2 subunit. Clone AK7 inhibits cell attachment to collagen.
Purification Affinity Chromatography on Protein G.
Alternative Name CD49b / ITGA2 (ITGA2 Antibody Abstract)
Background CD49b is a 160kD glycoprotein that non-covalently associates with the 130kD integrin beta 1 subunit to form the VLA-2 complex. CD49b is expressed by platelets, long term cultivated T cells, approximately 50 % of monocytes and most adherent cell lines.Synonyms: CD49 antigen-like family member B, Collagen Receptor, GPIa, ITGA-2, Integrin alpha-2, Platelet membrane glycoprotein Ia, VLA-2 alpha, VLA2
Gene ID 3673
NCBI Accession NP_002194
UniProt P17301
Research Area CD Antigens, Surface Receptors of Immune Cells, Cell/Tissue Markers, Extracellular Matrix, Signaling
Pathways CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
Application Notes Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.1 mg/mL
Buffer PBS containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Mazurov, Vinogradov, Kabaeva, Antonova, Romanov, Vlasik, Antonov, Smirnov: "A monoclonal antibody, VM64, reacts with a 130 kDa glycoprotein common to platelets and endothelial cells: heterogeneity in antibody binding to human aortic endothelial cells." in: Thrombosis and haemostasis, Vol. 66, Issue 4, pp. 494-9, 1992 (PubMed).

Favaloro, Moraitis, Bradstock, Koutts: "Co-expression of haemopoietic antigens on vascular endothelial cells: a detailed phenotypic analysis." in: British journal of haematology, Vol. 74, Issue 4, pp. 385-94, 1990 (PubMed).