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  • 产品名称：anti-HLAClassIIDQantibody(Biotin)

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  • 产品厂商：Acris-antibodies
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简单介绍：
anti-HLAClassIIDQantibody(Biotin)
详情介绍：
Immunogen Stimulated human B lymphocytes. The antigen is HLA-DQ. The epitope has not been further characterized.
Clone FN81
Isotype IgG2a
Cross-Reactivity (Details) Species reactivity (tested):Human.
Characteristics Synonyms: HLA-DQ, HLA class II histocompatibility antigen DQ, MHC class II antigen DQ, majorhistocompatibility complex class II
Purification Affinity Chromatography.
Background HLA-DQ is an HLA class II antigen with homology to murine H-2A. HLA class II antigens are mainly expressed on specialized antigen presenting cells (APCs), dendritic cells, B-cells and macrophages. HLA class II antigen is presented on activated T-cells. HLA class II molecules present exogenously derived antigen to the T-cell receptor (TCR) on CD4+ T lymphocytes. Both chains in HLA-DQ are polymorphic. HLA-DQ is expressed after DR and DP during haemotopoietic progenitor cell development. It is strongly expressed in the thymic cortex.Synonyms: MHC Class II DQ
Research Area Major Histocompatibility Complex (MHC)
Application Notes Immunohistochemistry on Frozen Sections:
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Reconstitution Restore with 0.5 mL distilled water (= Stock solution).
Concentration 0.2 mg/mL
Buffer PBS, pH 7.2, with 0.05 % Kathon as preservative and 5 mg/mL BSA as stabilizer.
Preservative Kathon CG
Precaution of Use This product contains Kathon CG a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store lyophilized at 2-8 °C. Stock solution or aliquots of stock solution can be kept frozen at -20 °C. Do not freeze working dilutions. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months
Supplier Images
Immunohistochemistry (IHC) image for anti-HLA Class II DQ antibody (Biotin) (ABIN452105) anti-HLA Class II DQ antibody (Biotin)
Background publications Ishikura, Ishikawa, Aizawa: "Differential expression of HLA-class II antigens in the human thymus. Relative paucity of HLA-DQ antigens in the thymic medulla." in: Transplantation, Vol. 44, Issue 2, pp. 314-7, 1987 (PubMed).

Symington, Levine, Braun, Brown, Erlich, Torok-Storb: "Differential Ia antigen expression by autologous human erythroid and B lymphoblastoid cell lines." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 135, Issue 2, pp. 1026-32, 1985 (PubMed).

Guy, Van Heyningen, Cohen, Deane, Steel: "Differential expression and serologically distinct subpopulations of human Ia antigens detected with monoclonal antibodies to Ia alpha and beta chains." in: European journal of immunology, Vol. 12, Issue 11, pp. 942-8, 1983 (PubMed).