产品详情
所在位置: 首页> 产品目录> 一抗>
查看大图

  • 产品名称：anti-CD24antibody(CD24Molecule)(FITC)

  • 产品型号：
  • 产品厂商：Acris-antibodies
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
anti-CD24antibody(CD24Molecule)(FITC)
详情介绍：
Clone 91
Isotype IgG2a
Specificity This antibody is specific to Heat Stable Antigen HSA (Mr 35-45 kDa).
Characteristics Synonyms: X62 heat stable antigen, HSA, Signal transducer CD24, Small cell lung carcinoma cluster 4antigen
Alternative Name CD24 (CD24 Antibody Abstract)
Background CD24, also known as heat stable antigen, is a phosphatidylinositol-linked cell surface glycoprotein that is expressed at all stages of B cell development and on most thymocytes. (Ref.1-3) The absence of expression from mature T cells is closely associated with their maturation from CD4+CD8+CD24+ thymocytes to either CD4+CD8-CD24- or CD4-CD8+CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. (Ref.4-6) Its ligand is P-selectin (CD62P). (Ref.7) CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes. (Ref.1-3). The monoclonal antibody 91 can be used to inhibit B-cell differentiation. (Ref.8)Synonyms: HSA, Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen, X62 heat stable antigen
Gene ID 12484
UniProt P24807
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
Application Notes Flow Cytometry: < / = 4 μg/10^6 cells. (Ref.8)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS containing 0.09 % Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months
Supplier Images
Flow Cytometry (FACS) image for anti-CD24 antibody (CD24 Molecule) (FITC) (ABIN370873) anti-CD24 Molecule (CD24) antibody (FITC)
Background publications Aigner, Ruppert, Hubbe, Sammar, Sthoeger, Butcher, Vestweber, Altevogt: "Heat stable antigen (mouse CD24) supports myeloid cell binding to endothelial and platelet P-selectin." in: International immunology, Vol. 7, Issue 10, pp. 1557-65, 1996 (PubMed).

Rougon, Alterman, Dennis, Guo, Kinnon: "The murine heat-stable antigen: a differentiation antigen expressed in both the hematolymphoid and neural cell lineages." in: European journal of immunology, Vol. 21, Issue 6, pp. 1397-402, 1991 (PubMed).

Alterman, Crispe, Kinnon: "Characterization of the murine heat-stable antigen: an hematolymphoid differentiation antigen defined by the J11d, M1/69 and B2A2 antibodies." in: European journal of immunology, Vol. 20, Issue 7, pp. 1597-602, 1990 (PubMed).

Wilson, Day, Scollay, Shortman: "Subpopulations of mature murine thymocytes: properties of CD4-CD8+ and CD4+CD8- thymocytes lacking the heat-stable antigen." in: Cellular immunology, Vol. 117, Issue 2, pp. 312-26, 1989 (PubMed).

Scollay, Bartlett, Shortman: "T cell development in the ***** murine thymus: changes in the expression of the surface antigens Ly2, L3T4 and B2A2 during development from early precursor cells to emigrants." in: Immunological reviews, Vol. 82, pp. 79-103, 1985 (PubMed).

Bruce, Symington, McKearn, Sprent: "A monoclonal antibody discriminating between subsets of T and B cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 127, Issue 6, pp. 2496-501, 1982 (PubMed).

Davidson, Chused, Morse: "Genetic control of B- and T-lymphocyte abnormalities of NZB mice in crosses with B10.D2 mice." in: Immunogenetics, Vol. 13, Issue 5, pp. 421-34, 1982 (PubMed).