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  • 产品名称：FibroblastGrowthFactor7(FGF7)(Active)Protein

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  • 产品厂商：SXBIO
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简单介绍：
FibroblastGrowthFactor7(FGF7)(Active)Protein
详情介绍：
Sequence CNDMTPEQMA TNVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNNYNIMEIR TVAVGIVAIK GVESEFYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHNGG EMFVALNQKG IPVRGKKTKK EQKTAHFLPM AIT
Characteristics Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 10 ng/mL, corresponding to a specific activity of ＞ 1.0 x 105 IU/mg.
Purity >96?% as determined by SDS-PAGE and HPLC.
Sterility 0.2 μm filtered
Background Relevance: Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation. {ECO:0000269|PubMed:16597617, ECO:0000269|PubMed:8663044}.
Synonyms: FGF-7, HBGF-7, Keratinocyte growth factor
Molecular Weight 18.9 kDa
UniProt P21781
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Restrictions For Research Use only
Format Lyophilized
Buffer 20 mM PB, 0.5 M NaCl,?pH 8.0
Storage -20 °C