产品详情
查看大图

  • 产品名称：ColonyStimulatingFactor1(Macrophage)(CSF1)(Active)Protein

  • 产品型号：
  • 产品厂商：SXBIO
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
ColonyStimulatingFactor1(Macrophage)(CSF1)(Active)Protein
详情介绍：
Sequence KEVSEHCSHM IGNGHLKVLQ QLIDSQMETS CQIAFEFVDQ EQLDDPVCYL KKAFFLVQDI IDETMRFKDN TPNANATERL QELSNNLNSC FTKDYEEQNK ACVRTFHETP LQLLEKIKNF FNETKNLLEK DWNIFTKNCN NSFAKCSSRD VVTKPDCNCL YPKATPSSDP ASASPHQPPA PSMAPLAGLA WDDSQRTEGS SLLPSELPLR IEDPGSAKQR PPRSTCQTLE
Characteristics Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine M-NFS-60 cells is less than 2 ng/mL, corresponding to a specific activity of ＞ 5.0 x 105 IU/mg.
Purity >95 % as determined by SDS-PAGE and HPLC.
Sterility 0.2 μm filtered
Background Relevance: Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.
Synonyms: CSF-1,
Molecular Weight 52.0 kDa
UniProt P07141
Pathways RTK Signaling
Restrictions For Research Use only
Format Lyophilized
Buffer 20 mM Tris, 500 mM NaCl, pH 7.4
Storage -20 °C