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  • 产品名称：Amphiregulin(AREG)(Active)Protein

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  • 产品厂商：SXBIO
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简单介绍：
Amphiregulin(AREG)(Active)Protein
详情介绍：
Sequence SVRVEQVVKP PQNKTESENT SDKPKRKKKG GKNGKNRRNR KKKNPCNAEF QNFCIHGECK YIEHLEAVTC KCQQEYFGER CGEKSMKTHS MIDSSLSK
Characteristics Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is between 5-10 ng/mL.
Purity >95 % as determined by SDS-PAGE and HPLC.
Sterility 0.2 μm filtered
Background Relevance: Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.
Synonyms: AR, CRDGF
Molecular Weight 11.3 kDa
UniProt P15514
Pathways RTK Signaling, EGFR Signaling Pathway
Restrictions For Research Use only
Format Lyophilized
Buffer PBS, pH 7.4
Storage -20 °C