产品详情
  • 产品名称:FibroblastGrowthFactor2(Basic)(FGF2)(Active)Protein

  • 产品型号:
  • 产品厂商:SXBIO
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简单介绍:
FibroblastGrowthFactor2(Basic)(FGF2)(Active)Protein
详情介绍:
Sequence MPALPEDGGS GAFPPGHFKD PKRLYCKNGG FFLRIHPDGR VDGVREKSDP HIKLQLQAEE RGVVSIKGVC ANRYLAMKED GRLLASKCVT DECFFFERLE SNNYNTYRSR KYTSWYVALK RTGQYKLGSK TGPGQKAILF LPMSAKS
Characteristics Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine balb/c 3T3 cells is less than 0.05 ng/mL, corresponding to a specific activity of > 2.0 x 107 IU/mg.
Purity >96 % as determined by SDS-PAGE and HPLC.
Sterility 0.2 μm filtered
Background Relevance: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. {ECO:0000269|PubMed:1721615, ECO:0000269|PubMed:8663044}.
Synonyms: FGF-2, bFGF, Heparin-binding growth factor 2, HBGF-2,
Molecular Weight 16.5 kDa
UniProt P09038
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus
Restrictions For Research Use only
Format Lyophilized
Buffer PBS, pH 7.4
Storage -20 °C